THE ROLE OF AFFECTIVE TEMPERAMENTS AND CHRONOTYPE IN PHARMACOTHERAPY RESPONSE IN PATIENTS WITH OBSESSIVE-COMPULSIVE DISORDER

The role of affective temperaments and chronotype in pharmacotherapy response in patients with obsessive-compulsive disorder

BACKGROUND: Comorbid mood disorders affect the prognosis of obsessive-compulsive disorder (OCD) negatively.Affective temperaments are assumed to be subsyndromal symptoms and precursors of mood disorders, but its effects on OCD outcome still remain unclear.There is a body of evidence, which supports the association between circadian rhythm operation

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A New Benzoyl Compound Isolated from the Endophytic Fungi of Kandis Gajah (Garcinia griffithii) and Asam Kandis (Garcinia cowa)

Garcinia griffithii and Garcinia cowa belong to the genus Garcinia.The genus Garcinia has been known to gauze fabric by the bolt be a rich source of secondary metabolites, such as xanthones, benzophenones, flavonoids, steroids, terpenoids, and other phenolic derivatives.Previous investigations of endophytic fungi from G.griffithii revealed the pres

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